Biography

My research focuses on the molecular mechanics underlying Ca²⁺ dysregulation in cardiac and skeletal muscle. I received her PhD at The John Curtin School of Medical Research, and after postdocs at Krannert Institute of Cardiology (USA) and The John Curtin School of Medical Research (Australia), took up a tenured position at the University of Canberra, Australia.

My research team investigate how intracellular calcium signalling pathways contribute to muscle contraction. We explore and define the mechanisms that lead to control of calcium signalling and the way in which these are disrupted in skeletal myopathies, cardiomyopathy and heart failure. A special focus of the team’s research is on the internal ryanodine receptor calcium release channel, and understanding how stress-induced post-translational modifications of the channel lead to aberrant calcium release during rest, and contribute to heart failure, arrhythmia and sarcopenia. I serve an academic editor on PLOS One, and chair of the Gage Conferences in Muscle Contraction.